There already exist non-opioid painkillers, such as ibuprofen, paracetamol, and aspirin; however, they may not be appropriate for more severe forms of acute pain. This is why there is a need for ...

As we start looking to the year ahead, the pharma industry is gearing up for a slate of new drug launches and U.S. Food and ...

The No Pain Act will mandate Medicare insurance coverage for non-opioid pain management, including evidence-based treatments, ...

Objective To review qualitative studies on the experience of taking opioid medication for chronic non-malignant pain (CNMP) or coming off them. Design This is a qualitative evidence synthesis using a ...

their deep-learning framework identified several gut microbiome-derived metabolites along with U.S. Food and Drug Administration (FDA)-approved drugs that can be repurposed to select non-addictive, ...

When the researchers administered naloxone, a drug that blocks both synthetic and endogenous ... indicating that women rely ...

Opioids have long been used to treat severe pain, though their use in the management of chronic pain remains somewhat controversial. Some people can tolerate opioids for years without any adverse ...

Nearly three quarters of new non-cancer pain opioid prescriptions were for patients with musculoskeletal conditions, despite limited evidence of the drug's efficacy, according to the largest U.K ...